Double-crowned valved stents for off-pump mitral valve replacement☆

Double-crowned valved stents for off-pump mitral valve replacement.

OBJECTIVE An animal model has been designed to assess the feasibility of off-pump mitral valve replacement using valved stents. METHODS Glutaraldehyde-preserved homograft was sutured inside a prosthetic tube (Dacron). Then, two self-expandable nitinol Z-stents were sutured on the external surface of the prosthesis in such a way to create two self-expanding crowns for fixation. In adult pigs a...

Percutaneous pulmonary valve replacement: autologous tissue-engineered valved stents.

AIMS Percutaneous implantation has already been used clinically and is a great option for treating young patients. The use of autologous tissue-engineered valved stents might solve the problem of degeneration and limited durability of biological heart valves. METHODS AND RESULTS Porcine pulmonary heart valves and small intestinal submucosa were obtained from a slaughterhouse. The intestinal s...

One-stage off-pump transapical mitral valve repair and aortic valve replacement.

Double Valve Replacement (Mitral and Aortic) for Rheumatic Heart Disease: A 20-year experience with 300 patients.

Introduction: Rheumatic heart disease still remains one of the leading causes of congestive heart failure and death owing to valvular pathologies, in developing countries. Valve replacement still remains the treatment of choice in such patients.The aim of this study wasto analyze the postoperative outcome of  double valve replacement (Mitral and Aortic ) in patients of rheumatic heart disease. ...

Off-pump transapical mitral valve-in-ring implantation.

OBJECTIVES The study aimed to evaluate the feasibility of off-pump transapical mitral valve-in-ring implantation and to test the performance of a custom-made self-expandable stent valve, in comparison with the standard SAPIEN valve. METHODS Acute experiments were performed in five pigs. Animals (mean weight 58.4 ± 7.3 kg) underwent mitral valve annuloplasties under cardiopulmonary bypass usin...